For a free electronic reprint of any Burke Group publication, please email Ramona Rudzinski at ramonar@illinois.edu
103. SynerGPT: In-Context Learning for Personalized Drug Synergy Prediction and Drug Design, Carl Edwards, Aakanksha Naik, Tushar Khot, Martin D. Burke, Heng Ji and Tom Hope, 2023, arXiv.
102. Property-Guided Generative Modelling for Robust Model-Based Design with Imbalanced Data, Saba Ghaffari, Ehsan Saleh, Alexander G. Schwing, Yu-Xiong Wang, Martin D. Burke, & Saurabh Sinha, 2023, arXiv preprint arXiv:2305.13650.
101. Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling, Nicholas H. Angello, Vandana Rathore, Wiktor Beker, Agnieszka Wołos, Edward R. Jira, Rafał Roszak, Tony C. Wu, Charles M. Schroeder, Alán Aspuru-Guzik, Bartosz A. Grzybowski, Martin D. Burke, Science, 2022, 378, 399-405. DOI: https://doi.org/10.1021/acscatal.2c03245
100. Stereospecific Csp3 Suzuki-Miyaura Cross-Coupling That Evades b-Oxygen Elimination, Antonio J. LaPorte, Yao Shi, Jason E. Hein, and Martin D. Burke, ACS Catal. 2022, 12, 10905-10912
99. A rationally designed molecular prosthetic for cystic fibrosis, A Lewandowska, I Thornell, C Soutar, K Green, J Lange, D Miller, T Tarara, T Pogorelov, C Rienstra, M Welsh, J Weers, M Burke, J. Cystic Fibrosis 2022, 21, S337.
98. A dry powder aerosol comprising a small molecule prosthetic ion-channel for treatment of people with cystic fibrosis, D Miller, T Tarara, S Lyons, M Burke, A Lewandowska, C Soutar, J Weers, J. Cystic Fibrosis 2022, 21, S229.
97. A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages, Stella Ekaputria, Eun-Kyung Choi, Manuela Sabelli, Luisa Aring, Kelsie J. Green, JuOae Chang, Kai Bao, Hak Soo Choi, Shigeki Iwase, Jonghan Kim, Elena Corradini, Antonello Pietrangelo, Martin D. Burke and Young Ah Seo Proc. Natl. Acad. Sci. U.S.A. 2022, 119, e2121400119 https://doi.org/10.1073/pnas.2121400119
96. Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation, Nicole M. Revie, Kali R. Iyer, Michelle E. Maxson, Jiabao Zhang, Su Yan, Caroline M. Fernandes, Kirsten J. Meyer, Xuefei Chen, Iwona Skulska, Meea Fogal, Hiram Sanchez, Saif Hossain, Sheena Li, Yoko Yashiroda, Hiroyuki Hirano, Minoru Yoshida, Hiroyuki Osada, Charles Boone, Rebecca S. Shapiro, David R. Andes, Gerard D. Wright, Justin R. Nodwell, Maurizio Del Poeta, Martin D. Burke, Luke Whitesell, Nicole Robbins & Leah E. Cowen Nature Commun 2022, 13, 3634, https://doi.org/10.1038/s41467-022-31308-1
95. MIDA Anhydride and Reaction with Boronic Acids, Aidan M. Kelly, Peng-Jui Chen, Jenna Klubnick, Daniel J. Blair, and Martin D. Burke Org. Synth. 2022, 99, 92 DOI: 10.15227/orgsyn.099.0092
94. Digitizing Chemical Synthesis in 3D Printed Reactionware, Andrius Bubliauskas, Daniel J. Blair, Henry Powell-Davies, Philip J. Kitson, Martin D. Burke, Leroy Cronin, Angew. Chem. Int. Ed. 2022, e202116108; Angew. Chem. 2022, e202116108
93. Mitigation of SARS-CoV-2 Transmission at a Large Public University, Diana Rose E. Ranoa, Robin L. Holland, Fadi G. Alnaji, Kelsie J. Green, Leyi Wang, Richard L. Fredrickson, Tong Wang, George N. Wong, Johnny Uelmen, Sergei Maslov, Ahmed Elbanna, Zachary J. Weiner, Alexei V. Tkachenko, Hantao Zhang, Zhiru Liu, Sanjay J. Patel, John M. Paul, Nickolas P. Vance, Joseph G. Gulick, Sandeep Puthanveetil Satheesan, Isaac J. Galvan, Andrew Miller, Joseph Grohens, Todd J. Nelson, Mary P. Stevens, P. Mark Hennessy, Robert C. Parker Jr, Edward Santos, Charles Brackett, Julie D. Steinman, Melvin R. Fenner Jr, Kirstin Dohrer, Kraig Wagenecht, Michael DeLorenzo, Laura Wilhelm-Barr, Brian R. Brauer, Catherine Best-Popescu, Gary Durack, Nathan Wetter, David M. Kranz, Jessica Breitbarth, Charlie Simpson, Julie A. Pryde, Robin N. Kaler, Chris Harris, Allison C. Vance, Jodi L. Silotto, Mark Johnson, Enrique Valera, Patricia K. Anton, Lowa Mwilambwe, Stephen P. Bryan, Deborah S. Stone, Danita B. Young, Wanda E. Ward, John Lantz, John A. Vozenilek, Rashid Bashir, Jeffrey S. Moore, Mayank Garg, Julian C. Cooper, Gillian Snyder, Michelle H. Lore, Dustin L. Yocum, Neal J. Cohen, Jan E. Novakofski, Melanie J. Loots, Randy L. Ballard, Mark Band, Kayla M. Banks, Joseph D. Barnes, Iuliana Bentea, Jessica Black, Jeremy Busch, Hannah Christensen, Abigail Conte, Madison Conte, Michael Curry, Jennifer Eardley, April Edwards, Therese Eggett, Judes Fleurimont, Delaney Foster, Bruce W. Fouke, Nicholas Gallagher, Nicole Gastala, Scott A. Genung, Declan Glueck, Brittani Gray, Andrew Greta, Robert M. Healy, Ashley Hetrick, Arianna A Holterman, Nahed Ismail, Ian Jasenof, Patrick Kelly, Aaron Kielbasa, Teresa Kiesel, Lorenzo M. Kindle, Rhonda L. Lipking, Yukari C. Manabe, Jade Mayes, Reubin McGuffin, Kenton G. McHenry, Agha Mirza, Jada Moseley, Heba H. Mostafa, Melody Mumford, Kathleen Munoz, Arika D. Murray, Moira Nolan, Nil A. Parikh, Andrew Pekosz, Janna Pflugmacher, Janise M. Phillips, Collin Pitts, Mark C. Potter, James Quisenberry, Janelle Rear, Matthew L. Robinson, Edith Rosillo, Leslie N. Rye, MaryEllen Sherwood, Anna Simon, Jamie M. Singson, Carly Skadden, Tina H. Skelton, Charlie Smith, Mary Stech, Ryan Thomas, Matthew A. Tomaszewski, Erika A. Tyburski, Scott Vanwingerden, Evette Vlach, Ronald S. Watkins, Karriem Watson, Karen C. White, Timothy L. Killeen, Robert J. Jones, Andreas C. Cangellaris, Susan A. Martinis, Awais Vaid, Christopher B. Brooke, Joseph T. Walsh, William C. Sullivan, Rebecca L. Smith, Nigel D. Goldenfeld, Timothy M. Fan, Paul J. Hergenrother, Martin D. Burke Nature Commun 2022, 13, 3207. https://doi.org/10.1038/s41467-022-30833-3
92. Using automated synthesis to understand the role of side chains on molecular charge transport, Songsong Li, Edward R. Jira, Nicholas H. Angello, Jialing Li, Hao Yu, Jeffrey S. Moore, Ying Diao, Martin D. Burke, and Charles M. Schroeder Nature Commun 2022, 13, 2102. https://doi.org/10.1038/s41467-022-29796-2
91. Automated iterative Csp3-C bond formation, Daniel J. Blair, Sriyankari Chitti, Melanie Trobe, David M. Kostyra, Hannah M. S. Haley, Richard L. Hansen, Steve G. Ballmer, Toby J. Woods, Wesley Wang, Vikram Mubayi, Michael J. Schmidt, Robert W. Pipal, Greg. F. Morehouse, Andrea M. E. Palazzolo Ray, Danielle L. Gray, Adrian L. Gill & Martin D. Burke Nature 2022, 604, 92-97. https://doi.org/10.1038/s41586-022-04491-w
90. A Materials Acceleration Platform for Organic Laser Discovery, Tony C. Wu, Andrés Aguilar Granda, Kazuhiro Hotta, Sahar Alasvand Yazdani, Robert Pollice, Jenya Vestfrid, Han Hao, Cyrille Lavigne, Martin Seifrid, Nicholas H. Angello, Fatima Bencheikh, Jason E. Hein, Martin D. Burke, Chihaya Adachi, Alán Aspuru-Guzik Advanced Materials, 2022, in press; ChemRxiv. Cambridge: Cambridge Open Engage; 2022 DOI 10.26434/chemrxiv-2022-9zm65
89. Automated Synthesis for Single-Molecule Electronics, Edward R. Jira, Songsong Li, Nicholas H. Angello, Jialing Li, Jeffrey S. Moore, Martin D. Burke, Charles M. Schroeder Bulletin of the American Physical Society, 2022
88. Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki-Miyaura Coupling, Wiktor Beker, Rafał Roszak, Agnieszka Wołos, Nicholas H. Angello, Vandana Rathore, Martin D. Burke, and Bartosz A. Grzybowski J. Am. Chem. Soc. 2022, 144, 11, 4819–4827 https://doi.org/10.1021/jacs.1c12005
87. Iterations from the chemical cosmos, Danielle C. Loving and Martin D. Burke Nature Synth 1, 11–12 2022, https://doi.org/10.1038/s44160-021-00014-z
86. Saliva-based molecular testing for sars-cov-2, Diana Rose Ranoa, Robin L Holland, Fadi G Alnaji, Kelsie J Green, Leyi Wang, Christopher B Brooke, Martin D Burke, Timothy M Fan, Paul J Hergenrother US Patent App. 17/636,469
85. Validation of a molecular assay to detect SARS-CoV-2 in saliva, Janet L. Pitman, Arthur J. Morris, Stephen Grice, Joseph T. Walsh, Leyi Wang, Martin D. Burke, Amanda Dixon-McIver The New Zealand Medical Journal, 2021, 134, 1547.
84. Chemical-reaction-aware molecule representation learning, Hongwei Wang, Weijiang Li, Xiaomeng Jin, Kyunghyun Cho, Heng Ji, Jiawei Han, Martin D. Burke arXiv 2021; https://arxiv.org/abs/2109.09888
83. Hybrid amphotericin B derivatives with reduced toxicity, Martin D. Burke, Anuj Khandelwal, Jiabao Zhang, Anna SantaMaria, US Patent 11,198,705. 2021
82. Fungicidal Amphotericin B Sponges are Assemblies of Staggered Asymmetric Homodimers Encasing Large Void Volumes, Agnieszka Lewandowska, Corinne P. Soutar, Alexander I. Greenwood, Evgeny Nimerovsky, Ashley M. De Lio, Jordan T. Holler, Grant S. Hisao, Anuj Khandelwal, Jiabao Zhang, Anna M. SantaMaria, Charles D. Schwieters, Taras V. Pogorelov, Martin D. Burke & Chad M. Rienstra Nature Structural & Molecular Biology 2021, 12, 972-981 DOI: 10.1038/s41594-021-00685-4
81. Transition between Nonresonant and Resonant Charge Transport in Molecular Junctions, Songsong Li, Hao Yu, Jialing Li, Nicholas Angello, Edward R. Jira, Bo Li, Martin D. Burke, Jeffrey S. Moore, and Charles M. Schroeder Nano Letters 2021, 21 (19), 8340-8347 DOI: 10.1021/acs.nanolett.1c02915
80. Well-Tolerated Amphotericin B Derivatives That Effectively Treat Visceral Leishmaniasis, Christelle Morelle, Angana Mukherjee, Jiabao Zhang, Fereshteh Fani, Anuj Khandelwal, Hélène Gingras, Jocelyn Trottier, Olivier Barbier, Philippe Leprohon, Martin D. Burke, and Marc Ouellette ACS Infectious Diseases 2021, 7 (8), 2472-2482 DOI: 10.1021/acsinfecdis.1c00245
79. Sterol Sponge Mechanism Is Conserved for Glycosylated Polyene Macrolides, Xiaorui Guo, Jiabao Zhang, Xinyi Li, Emily Xiao, Justin D. Lange, Chad M. Rienstra, Martin D. Burke, and Douglas A. Mitchell ACS Central Science 2021 7 (5), 781-791 DOI: 10.1021/acscentsci.1c00148
78. Amphotericin B induces epithelial voltage responses in people with cystic fibrosis, Rajeev S. Chorghade, Bo Ram Kim, Janice L. Launspach, Philip H. Karp, Michael J. Welsh and Martin D. Burke Journal of Cystic Fibrosis 2020, 7 (5), 781-791 DOI: 10.1016/j.jcf.2020.11.01
77. COVID-19 Testing Strategies for Colleges and Universities National Academies of Sciences, Engineering, and Medicine.’ Washington, DC: The National Academies Press, 2020
76. Saliva-Based Molecular Testing for SARS-CoV-2 that Bypasses RNA Extraction, Diana Rose E. Ranoa, Robin L. Holland, Fadi G. Alnaji, Kelsie J. Green, Leyi Wang, Christopher Byron Brooke, Martin D. Burke, Timothy M. Fan, Paul Hergenrother Cold Spring Harbor Laboratory Press, 2020 DOI: 10.1101/2020.06.18.159434v1
75. Derivatives of Amphotericin B, Martin D. Burke, Arun P. Thottumkara, Kevin T. Mellem, Zachary K. Sweeney, Elena S. Koltun, US Patent 10,882,883. 2021
74. Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance, Daniel J. Blair and Martin D. Burke Nature 2020 586, 32-33 DOI: 10.1038/d41586-020-02565-1
73. A Mild Method for Making MIDA Boronates, Aidan M. Kelly, Peng-Jui Chen, Jenna Klubnick, Daniel J. Blair, and Martin D. Burke Organic Letters 2020, 22 (24), 9408-9414 DOI: 10.1021/acs.orglett.0c02449
72. Small Molecule Channels Harness Membrane Potential to Concentrate Potassium in trk1Δtrk2Δ Yeast, Jennifer Hou, Page N. Daniels, and Martin D. Burke ACS Chemical Biology 2020, 15 (6), 1575-1580 DOI: 10.1021/acschembio.0c00180
71. A Computer Conquers Tactical Combinations, Daniel J. Blair and Martin D. Burke Chem. 2020, 6 (1), 12-13 DOI: 10.1016/j.chempr.2019.12.019
70. Stereoretentive Cross-coupling Of Boronic Acids, Martin D. Burke, Ian Crouch, Jonathan Lehmann, Andrea Palazzolo, Claire Simons, US Patent 10,370,393. 2019
69. Amphotericin B derivatives with improved therapeutic index, Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, US Patent 10,323,057. 2019
68. Modular Syntheses of Phenanthroindolizidine Natural Products, Young-In Jo, Martin D. Burke, and Cheol-Hong Cheon Organic Letters 2019, 21 (11), 4201-4204 DOI: 10.1021/acs.orglett.9b01397
67. Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids, Jonathan W. Lehmann, Ian T. Crouch, Daniel J. Blair, Melanie Trobe, Pulin Wang, Junqi Li and Martin D. Burke Nature Communications 2019, 10, 1263 DOI: 10.1038/s41467-019-09249-z
66. Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia, Katrina A. Muraglia, Rajeev S. Chorghade, Bo Ram Kim, Xiao Xiao Tang, Viral S. Shah, Anthony S. Grillo, Page N. Daniels, Alexander G. Cioffi, Philip H. Karp, Lingyang Zhu, Michael J. Welsh and Martin D. Burke Nature 2019, 567, 405–408 DOI: 10.1038/s41586-019-1018-5
65. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity, Yvette Y. Yien, Jiahai Shi, Caiyong Chen, Jesmine T.M. Cheung, Anthony S. Grillo, Rishna Shrestha, Liangtao Li, Xuedi Zhang, Martin D. Kafina, Paul D. Kingsley, Matthew J. King, Julien Ablain, Hojun Li, Leonard I. Zon, James Palis, Martin D. Burke, Daniel E. Bauer, Stuart H. Orkin, Carla M. Koehler, John D. Phillips, Jerry Kaplan, Diane M. Ward, Harvey F. Lodish and Barry H. Paw Journal of Biological Chemistry 2018, 293, 19797-19811. DOI: 10.1074/jbc.RA118.002742
64. Peridinin Is an Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation, Hannah M.S. Haley, Adam G. Hill, Alexander I. Greenwood, Eric M. Woerly, Chad M. Rienstra, and Martin D. Burke Journal of the American Chemical Society 2018, 140 (45), 15227-15240 DOI: 10.1021/jacs.8b06933
63. Scalable synthesis of reduced toxicity derivative of amphotericin B, Martin D. Burke, Brice E. Uno, Souvik Rakshit, US Patent 10,087,206. 2018
62. Derivatives of amphotericin B, Martin D. Burke, Arun P. Thottumkara, Kevin T. Mellem, Zachary K. Sweeney, Elena S. Koltun, US Patent 9,957,290. 2018
61. The molecular industrial revolution: automated synthesis of small molecules, Melanie Trobe and Martin D. Burke Angewandte Chemie 2018, 57, 4192-4214 DOI: 10.1002/anie.201710482
60. Solid-State NMR of highly 13C-enriched cholesterol in lipid bilayers Lisa A. Della Ripa, Zoe A. Petros, Alexander G. Cioffi, Dennis W. Piehl, Joseph M. Courtney, Martin D. Burke and Chad M. Rienstra Methods 2018, 138-139; 47-53. DOI: 10.1016/j.ymeth.2018.01.00
59. Methods for forming protected organoboronic acids, Martin D. Burke, Graham R. Dick, David M. Knapp, Eric P. Gillis, Jenna A. Klubnick, US Patent 9,908,900. 2018
58. Towards the generalized iterative synthesis of small molecules, Jonathan W. Lehmann, Daniel J. Blair and Martin D. Burke Nature Reviews Chemistry 2018, 2, 0115 DOI: 10.1038/s41570-018-0115
57. Slow release of organoboronic acids in cross-coupling reactions, Martin D. Burke, David M. Knapp, Eric P. Gillis, US Patent 9,845,317. 2017
56. Amphotericin B derivative with reduced toxicity, Martin D. Burke, Brice E. Uno, US Patent 9,738,677. 2017
55. The Natural Productome, Andrea M. E. Palazzolo, Claire L. W. Simons, Martin D. Burke Proceedings of the National Academy of Sciences 2017, 114 (22) 5564-5566; DOI: 10.1073/pnas.1706266114
54. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals, Anthony S. Grillo, Anna M. SantaMaria, Martin D. Kafina, Alexander G. Cioffi, Nicholas C. Huston, Murui Han, Young Ah Seo, Yvette Y. Yien, Christopher Nardone, Archita V. Menon, James Fan, Dillon C. Svoboda, Jacob B. Anderson, John D. Hong, Bruno G. Nicolau, Kiran Subedi, Andrew A. Gewirth, Marianne Wessling-Resnick, Jonghan Kim, Barry H. Paw and Martin D. Burke Science, 2017, 356 608-615. DOI: 10.1126/science.aah3862
53. MIDA Boronates Are Hydrolysed Fast and Slow by Two Different Mechanisms, Jorge A. Gonzalez, O. Maduka Ogba, Gregory F. Morehouse, Nicholas Rosson, Kendall N. Houk, Andrew G. Leach, Paul H.-Y. Cheong, Martin D. Burke and Guy C. Lloyd-Jones. Nature Chemistry 2016, 8, 1067-1075. DOI: 10.1038/nchem.2571
52. Automated synthesis of small molecules using chiral, non-racemic boronates, Martin D. Burke, Junqi Li, Eric P. Gillis, US Patent 9,388,131. 2016
51. Methods for forming protected organoboronic acids, Martin D. Burke, Graham R. Dick, David M. Knapp, Eric P. Gillis, Jenna A. Klubnick, US Patent 9,353,131. 2016
50. Slow release of organoboronic acids in cross-coupling reactions, Martin D. Burke, David M. Knapp, Eric P. Gillis, US Patent 9,328,102. 2016
49. System for controlling the reactivity of boronic acids, Martin D. Burke, Eric P. Gillis, US Patent 9,328,127. 2016
48. Our Path to Less Toxic Amphotericins, Matthew M. Endo Alexander G. Cioffi, Martin D. Burke Synlett 2015, 27, 337. DOI: 10.1055/s-0035-1560800 Recipient of the Thieme IUPAC Prize in Synthetic Organic Chemistry.
47. Apparatus and methods for the automated synthesis of small molecules, Martin D. Burke, Eric P. Gillis, Steven G. Ballmer, US Patent 9,238,597. 2016
46. C3-OH of Amphotericin B Plays an Important Role in Ion Conductance, Stephen A. Davis, Lisa A. Della Ripa, Lingbowei Hu, Alexander G. Cioffi, Taras V. Pogorelov, Chad M. Rienstra, and Martin D. Burke Journal of the American Chemical Society 2015 137 (48), 15102-15104 DOI: 10.1021/jacs.5b05766
45. Restored Physiology in Protein-Deficient Yeast by a Small Molecule Channel, Alexander G. Cioffi, Jennifer Hou, Anthony S. Grillo, Katrina A. Diaz, and Martin D. Burke Journal of the American Chemical Society 2015 137 (32), 10096-10099 DOI: 10.1021/jacs.5b05765
44. Nontoxic Antimicrobials that Evade Drug Resistance, Stephen A. Davis, Benjamin M. Vincent, Matthew M. Endo, Luke Whitesell, Karen Marchillo, David R. Andes, Susan Lindquist and Martin D. Burke. Nature Chemical Biology 2015, 11, 481-487. DOI: 10.1038/nchembio.1821
43. Automated synthesis of small molecules using chiral, non-racemic boronates, Martin D. Burke, Junqi Li, Eric P. Gillis, US Patent 9,012,658. 2015
42. Slow release of organoboronic acids in cross-coupling reactions, Martin D. Burke, David M. Knapp, Eric P. Gillis, US Patent 9,006,463. 2015
41. Synthesis of many different types of organic small molecules using one automated process, Junqi Li, Steven G. Ballmer, Eric P. Gillis, Seiko Fujii, Michael J. Schmidt, Andrea M. E. Palazzolo, Jonathan W. Lehmann, Greg F. Morehouse, and Martin D. Burke Science 2015, 347, 1221-1226 DOI: 10.1126/science.aaa5414
40. From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks, Junqi Li, Anthony S. Grillo, and Martin D. Burke. Accounts of Chemical Research 2015 48 (8), 2297-2307 DOI: 10.1021/acs.accounts.5b00128
39. Cyclopropyl PIDA boronate, M Duncton, Martin D. Burke, US Patent 8,754,251. 2014
38. Synthesis of Most Polyene Natural Product Motifs Using Just Twelve Building Blocks and One Coupling Reaction, Eric M. Woerly, Jahnabi Roy, Martin D. Burke. Nature Chemistry 2014, 6, 484-491. DOI: 10.1038/nchem.1947
37. Amphotericin Forms an Extramembranous and Fungicidal Sterol Sponge, Thomas M. Anderson, Mary C. Clay, Alexander G. Cioffi, Katrina A. Diaz, Grant S. Hisao, Marcus D. Tuttle, Andrew J. Nieuwkoop, Gemma Comellas, Nashrah Maryum, Shu Wang, Brice E. Uno, Erin L. Wildeman, Tamir Gonen, Chad M. Rienstra, Martin D. Burke. Nature Chemical Biology 2014, 10, 400-406. DOI: 10.1038/nchembio.1496
36. Methods for forming protected organoboronic acids, Martin D. Burke, Graham R. Dick, David M. Knapp, Eric P. Gillis, Jenna A. Klubnick, US Patent 8,557,980. 2013
35. (1-Bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Eric M. Woerly, Jonathan E. Miller, and Martin D. Burke Tetrahedron 2013, 69, 7732-7740. DOI: 10.1016/j.tet.2013.05.050
34. C2′-OH of Amphotericin B Plays an Important Role in Binding the Primary Sterol of Human Cells but Not Yeast Cells, Brandon C. Wilcock, Matthew M. Endo, Brice E. Uno, and Martin D. Burke Journal of the American Chemical Society 2013 135 (23), 8488-8491 DOI: 10.1021/ja403255s
33. Slow release of organoboronic acids in cross-coupling reactions, Martin D. Burke, David M. Knapp, Eric P. Gillis, US Patent 8,338,601. 2012
32. Electronic tuning of site-selectivity, Brandon C Wilcock 1, Brice E. Uno, Gretchen L. Bromann, Matthew J. Clark, Thomas M. Anderson and Martin D. Burke Nature Chemistry 2012, 4, 996-1003. DOI: 10.1038/nchem.1495
31. Amphotericin primarily kills yeast by simply binding ergosterol, Kaitlyn C. Gray, Daniel S. Palacios, Ian Dailey, Matthew M. Endo, Brice E. Uno, Brandon C. Wilcock, and Martin D. Burke Proceedings of the National Academy of Sciences U.S.A. 2012, 109, 2234-223 DOI: 10.1073/pnas.1117280109
30. A General Solution for the 2-Pyridyl Problem, Graham R. Dick, Eric M. Woerly and Martin D. Burke, Angewandte Chemie International Edition 2012, 51, 2667-2672 DOI: 10.1002/anie.201108608
29. Pinene-Derived Iminodiacetic Acid (PIDA): A Powerful Ligand for Stereoselective Synthesis and Iterative Cross-Coupling of C(sp3) Boronate Building Block, Junqi Li and Martin D. Burke Journal of the American Chemical Society 2011, 133 (35), 13774-13777 DOI: 10.1021/ja205912y
28. System for controlling the reactivity of boronic acids, Martin D. Burke, Eric P. Gillis, Suk Joong Lee, David M. Knapp, Kaitlyn C. Gray, US Patent 8,013,203. 2011
27. Total Synthesis of Synechoxanthin through Iterative Cross-Coupling, Seiko Fujii, Stephanie Y. Chang and Martin D. Burke Angewandte Chemie International Edition 2011, 50, 7862-7864. DOI: 10.1002/anie.201102688
26. Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities, Daniel S. Palacios, Ian Dailey, David M. Siebert, Brandon C. Wilcock, and Martin D. Burke Proceedings of the National Academy of Sciences U.S.A. 2011, 108, 6733-6738. DOI: 10.1073/pnas.1015023108
25. (Z)-(2-Bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Eric M. Woerly, Justin R. Struble, Nagarjuna Palyam, Sean P. O’Hara, and Martin D. Burke Tetrahedron 2011, 67, 4333-4343. DOI: 10.1016/j.tet.2011.04.021
24. A Simple and General Platform for Generating Stereochemically Complex Polyene Frameworks by Iterative Cross-Coupling, Suk Joong Lee, Thomas M. Anderson, Martin D. Burke Angewandte Chemie International Edition 2010, 49, 8860-8863. DOI: 10.1002/anie.201004911
23. Stereoretentive Suzuki−Miyaura Coupling of Haloallenes Enables Fully Stereocontrolled Access to (−)-Peridinin, Eric M. Woerly, Alan H. Cherney, Erin K. Davis, and Martin D. Burke Journal of the American Chemical Society 2010, 132 (20), 6941-6943 DOI: 10.1021/ja102721p
22. A General Method for Synthesis of 2-Heterocyclic N-Methyliminodiacetic Acid Boronates, Graham R. Dick, David M. Knapp, Eric P. Gillis, and Martin D. Burke Organic Letters 2010, 12 (10), 2314-2317 DOI: 10.1021/ol100671v
21. N-(Carboxymethyl)-N-methyl-glycine, Ian Dailey and Martin D. Burke Encyclopedia of Reagents for Organic Synthesis 2010, DOI: 10.1002/047084289X.rn01228
20. Ethynyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Graham R. Dick, David M. Knapp, Eric P. Gillis, and Martin D. Burke Tetrahedron 2010, 66, 4710-4718 DOI: 10.1016/j.tet.2010.04.020
19. A general solution for unstable boronic acids: Slow-release cross-coupling from air-stable MIDA boronates, David M. Knapp, Eric P. Gillis, Martin D. Burke Journal of the American Chemical Society, 2009 131(20), 6961-6963 DOI: 10.1021/ja901416p
18. Vinyl MIDA Boronate: a readily accessible and highly versatile building block for small molecule synthesis, Brice E. Uno, Eric P. Gillis, Martin D. Burke Tetrahedron 2009, 65, 3130-3138 DOI: 10.1016/j.tet.2010.04.020
17. Flexible tetracycline synthesis yields promising antibiotics, Martin D. Burke Nature Chemical Biology 2009, 5, 77-79 DOI: 10.1038/nchembio0209-77
16. B-Protected Haloboronic Acids for Iterative Cross-Coupling, Steven G. Ballmer, Eric P. Gillis, Martin D. Burke, Daniel Morton and Huw M.L. Davies Organic Syntheses 2009, 86, 344-359 DOI: 10.1002/0471264229.os086.33
15. Iterative Cross-Couplng with MIDA Boronates: Towards a General Platform for Small Molecule Synthesis, Eric P. Gillis and Martin D. Burke Aldrichimica Acta. 2009, 42(1): 17–27. DOI: 10.1002/0471264229.os086.33
14. Multistep Synthesis of Complex Boronic Acids from Simple MIDA Boronates, Eric P. Gillis and Martin D. Burke Journal of the American Chemical Society 2008, 130 (43), 14084-14085 DOI: 10.1021/ja8063759
13. Simple, Efficient, and Modular Syntheses of Polyene Natural Products via Iterative Cross-Coupling, Suk Joong Lee, Kaitlyn C. Gray, James S. Paek, and Martin D. Burke Journal of the American Chemical Society 2008, 130 (2), 466-468 DOI: 10.1021/ja078129x
12. A Post-PKS Oxidation of the Amphotericin B Skeleton Predicted to be Critical for Channel Formation Is Not Required for Potent Antifungal Activity, Daniel S. Palacios, Thomas M. Anderson, and Martin D. Burke Journal of the American Chemical Society 2007, 129 (45), 13804-13805 DOI: 10.1021/ja075739o
11. A Simple and Modular Strategy for Small Molecule Synthesis: Iterative Suzuki−Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks, Eric P. Gillis and Martin D. Burke Journal of the American Chemical Society 2007, 129 (21), 6716-6717 DOI: 10.1021/ja0716204
10. Molecular Prosthetics: Replicating the Functions of the Molecules of Life, Martin D. Burke Enhancing Chemistry Conference sponsored by the American Chemical Society. University of Illinois at Urbana-Champaign, Urbana, Illinois, March 17, 2006.
9. A Synthesis Strategy Yielding Skeletally Diverse Small Molecules Combinatorically, Martin D. Burke, Eric M. Berger, and Stuart L. Schreiber Journal of the American Chemical Society 2004 126 (43), 14095-14104 DOI: 10.1021/ja0457415
8. A planning strategy for diversity-oriented synthesis, Martin D. Burke and Stuart L. Schreiber Angewandte Chemie International Edition 2004, 43, 46-58. DOI: 10.1002/anie.200300626
7. Generating Diverse Skeletons of Small Molecules Combinatorially, Martin D. Burke, Eric M. Berger, and Stuart L. Schreiber Science 2003, 302, 613-618 DOI: 10.1126/science.1089946
6. Chemoenzymatic Route to Macrocyclic Hybrid Peptide/Polyketide-like Molecules, Rahul M. Kohli, Martin D. Burke, Junhua Tao, and Christopher T. Walsh Journal of the American Chemical Society 2003, 125 (24), 7160-7161 DOI: 10.1021/ja0352202
5. Teaching Target-Oriented and Diversity-Oriented Organic Synthesis at Harvard University, Martin D. Burke and Gojko Lalic Chemistry and Biology 2002, 9, 535-541. DOI: 10.1016/S1074-5521(02)00143-6
4. Conformationally restricted hybrid analogues of the hormone 1 alpha,25-dihydroxyvitamin D (3): design, synthesis, and biological evaluation, M. Christina White, Martin D. Burke, Sarah Peleg, Patrick Dolan, Thomas W. Kensler, Henry Brem, and Gary H. Posner Bioorganic & Medicinal Chemistry 2001, 9, 1691-1699 DOI: 10.1016/s0968-0896(01)00087-6
3. Central Nervous System, Drug Delivery to Treat, Martin D. Burke, Henry Brem, and Robert Langer in The Encyclopedia of Controlled Drug Delivery The Encyclopedia of Controlled Drug Delivery. Mathiowitz, E., Ed.; John Wiley and Sons., Vol. 1, 1999, 184-212.
2. Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation, Gary H. Posner, Jae Kyoo Lee, Qiang Wang, Sara Peleg, Martin D. Burke, Henry Brem, Patrick Dolan, and Thomas W. Kensler Journal of Medicinal Chemistry 1998, 41 (16), 3008-3014 DOI: 10.1021/jm980031t
1. Polymer-Controlled Drug Delivery: An Overview for the Clinician, Justin Hanes and Martin D. Burke. Hospital Pharmacist Report. December 1997 2-11.