Publications

  1. For a free electronic reprint of any Burke Group publication, please email Ramona Rudzinski at ramonar@illinois.edu

73. Using automated synthesis to understand the role of side chains on molecular charge transport, Li, S., Jira, E.R., Angello, N.H., Li, J., Yu, H., Moore, J.S., Diao, Y., Burke, M.D., Schroeder, C.M. Nat Commun 13, 2102. 2022, https://doi.org/10.1038/s41467-022-29796-2

72. Digitizing Chemical Synthesis in 3D Printed Reactionware, Blair DJ, Powell-Davies H, Kitson PJ, Burke MD, Cronin L. Acknow, Angew. Chem. Int. Ed. 2022, e202116108; Angew. Chem. 2022, e202116108.

71. A Materials Acceleration Platform for Organic Laser Discovery, Wu TC, Aguilar Granda A, Hotta K, Alasvand Yazdani S, Pollice R, Vestfrid J, Hao H, Lavigne C, Seifrid M, Angello N, Bencheikh F, Hein JE, Burke MD, Adachi C, Aspuru-Guzik A, ChemRxiv. Cambridge: Cambridge Open Engage; 2022 DOI 10.26434/chemrxiv-2022-9zm65

70. Automated Synthesis for Single-Molecule Electronics, Jira E, Li S, Angello N, Li J, Moore J, Burke MD, Schroeder C, Bulletin of the American Physical Society, 2022
 
69. Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki-Miyaura Coupling, Beker, W., Roszak, R., Wołos, A., Angello N.H., Rathore, V., Burke, M.D., Grzybowski, B. Journal of the American Chemical Society 2022, in press.
 

68. Automated iterative Csp3-C bond formation, Blair, D. J., Chitti, S., Trobe, M., Kostyra, D. M., Haley, H. M. S., Hansen, R. L., Ballmer, S. G., Woods, T. J., Wang, W., Mubayi, V., Schmidt, M. J., Pipal, R. W., Morehouse, G. F., Palazzolo Ray, A. M. E., Gray, D. L., Gill, A. L., & Burke, M. D. Nature 2022, https://doi.org/10.1038/s41586-022-04491-w

67. Iterations from the chemical cosmos, Loving, D.C., Burke, M.D.  Nature Synth 1, 11–12 2022, https://doi.org/10.1038/s44160-021-00014-z

66. Validation of a molecular assay to detect SARS-CoV-2 in saliva, Pitman JL, Morris AJ, Grice S, Walsh JT, Wang L, Burke MD, Dixon-McIver A, The New Zealand Medical Journal, Vol 134 No 1547: 17 2021

65. Chemical-Reaction-Aware Molecule Representation Learning, Hongwei Wang, Weijiang Li, Xiaomeng Jin, Kyunghyun Cho, Heng Ji, Jiawei Han and Martin D. Burke arXiv 2021

64. Mitigation of SARS-CoV-2 Transmission at a Large Public University, Diana Rose E. RanoaRobin L. HollandFadi G. AlnajiKelsie J. GreenLeyi WangRichard L. FredricksonTong WangGeorge N. WongJohnny UelmenSergei MaslovAhmed ElbannaZachary J. WeinerAlexei V. TkachenkoHantao ZhangZhiru LiuSanjay J. PatelJohn M. PaulNickolas P. VanceJoseph G. GulickSandeep Puthanveetil SatheesanIsaac J. GalvanAndrew MillerJoseph GrohensTodd J. NelsonMary P. StevensP. Mark HennessyRobert C. Parker JrEdward SantosCharles BrackettJulie D. SteinmanMelvin R. Fenner JrKirstin DohrerKraig WagenechtMichael DeLorenzoLaura Wilhelm-BarrBrian R. BrauerCatherine Best-PopescuGary DurackNathan WetterDavid M. KranzJessica BreitbarthCharlie SimpsonJulie A. PrydeRobin N. KalerChris HarrisAllison C. VanceJodi L. SilottoMark JohnsonEnrique ValeraPatricia K. AntonLowa MwilambweStephen P. BryanDeborah S. StoneDanita B. YoungWanda E. WardJohn LantzJohn A. VozenilekRashid BashirJeffrey S. MooreMayank GargJulian C. CooperGillian SnyderMichelle H. LoreDustin L. YocumNeal J. CohenJan E. NovakofskiMelanie J. LootsRandy L. BallardMark BandKayla M. BanksJoseph D. BarnesIuliana BenteaJessica BlackJeremy BuschHannah ChristensenAbigail ConteMadison ConteMichael CurryJennifer EardleyApril EdwardsTherese EggettJudes FleurimontDelaney FosterBruce W. FoukeNicholas GallagherNicole GastalaScott A. GenungDeclan GlueckBrittani GrayAndrew GretaRobert M. HealyAshley HetrickArianna A HoltermanNahed IsmailIan JasenofPatrick KellyAaron KielbasaTeresa KieselLorenzo M. KindleRhonda L. LipkingYukari C. ManabeJade MayesReubin McGuffinKenton G. McHenryAgha MirzaJada MoseleyHeba H. MostafaMelody MumfordKathleen MunozArika D. MurrayMoira NolanNil A. ParikhAndrew PekoszJanna PflugmacherJanise M. PhillipsCollin PittsMark C. PotterJames QuisenberryJanelle RearMatthew L. RobinsonEdith RosilloLeslie N. RyeMaryEllen SherwoodAnna SimonJamie M. SingsonCarly SkaddenTina H. SkeltonCharlie SmithMary StechRyan ThomasMatthew A. TomaszewskiErika A. TyburskiScott VanwingerdenEvette VlachRonald S. WatkinsKarriem WatsonKaren C. WhiteTimothy L. KilleenRobert J. JonesAndreas C. CangellarisSusan A. MartinisAwais VaidChristopher B. BrookeJoseph T. WalshWilliam C. SullivanRebecca L. SmithNigel D. GoldenfeldTimothy M. FanPaul J. HergenrotherMartin D. Burke medRxiv 2021.08.03.21261548; doi: https://doi.org/10.1101/2021.08.03.21261548

63. Fungicidal Amphotericin B Sponges are Assemblies of Staggered Asymmetric Homodimers Encasing Large Void Volumes, Agnieszka Lewandowska, Corinne P Soutar, Alexander I Greenwood, Evgeny Nimerovsky, Ashley M De Lio, Jordan T Holler 1, Grant S Hisao, Anuj Khandelwal, Jiabao Zhang, Anna M SantaMaria , Charles D Schwieters, Taras V Pogorelov, Martin D Burke, Chad M Rienstra Nature Structural & Molecular Biology 2021, 12, 972-981 DOI: 10.1038/s41594-021-00685-4

62. Well-Tolerated Amphotericin B Derivatives That Effectively Treat Visceral Leishmaniasis, Christelle Morelle, Angana Mukherjee, Jiabao Zhang, Fereshteh Fani, Anuj Khandelwal, Hélène Gingras, Jocelyn Trottier, Olivier Barbier, Philippe Leprohon, Martin D. Burke, and Marc Ouellette ACS Infectious Diseases 2021, 7 (8), 2472-2482 DOI: 10.1021/acsinfecdis.1c00245

61. Transition between Nonresonant and Resonant Charge Transport in Molecular Junctions, Songsong Li, Hao Yu, Jialing Li, Nicholas Angello, Edward R. Jira, Bo Li, Martin D. Burke, Jeffrey S. Moore, and Charles M. Schroeder Nano Letters 202121 (19), 8340-8347 DOI: 10.1021/acs.nanolett.1c02915

60.Sterol Sponge Mechanism Is Conserved for Glycosylated Polyene Macrolides, Xiaorui Guo, Jiabao Zhang, Xinyi Li, Emily Xiao, Justin D. Lange, Chad M. Rienstra, Martin D. Burke, and Douglas A. Mitchell ACS Central Science 2021 7 (5), 781-791 DOI: 10.1021/acscentsci.1c00148

59. Amphotericin B induces epithelial voltage responses in people with cystic fibrosis Rajeev S.Chorghade, Bo Ram Kim, Janice L. Launspach, Philip H.Karp, Michael J.Welsh and Martin D.Burke Journal of Cystic Fibrosis 2020, 7 (5), 781-791 DOI: 10.1016/j.jcf.2020.11.01

58. COVID-19 Testing Strategies for Colleges and Universities National Academies of Sciences, Engineering, and Medicine.’ Washington, DC: The National Academies Press, 2020

57. Saliva-Based Molecular Testing for SARS-CoV-2 that Bypasses RNA Extraction Diana Rose E Ranoa, Robin L. Holland, Fadi G. Alnaji, Kelsie J. Green, Leyi Wang, Christopher Byron Brooke, Martin Burke, Timothy M Fan, Paul Hergenrother Cold Spring Harbor Laboratory Press, 2020 DOI: 10.1101/2020.06.18.159434v1

56. Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance Daniel J Blair and Martin D Burke Nature 2020 586, 32-33 DOI: 10.1038/d41586-020-02565-1

55. A Mild Method for Making MIDA Boronates Aidan M. Kelly, Peng-Jui Chen, Jenna Klubnick, Daniel J. Blair, and Martin D. Burke Organic Letters 2020, 22 (24), 9408-9414 DOI: 10.1021/acs.orglett.0c02449

54. A Computer Conquers Tactical Combinations, Daniel J Blair and Martin D Burke Chem. 2020, 6 (1), 12-13 DOI: 10.1016/j.chempr.2019.12.019

53. Small Molecule Channels Harness Membrane Potential to Concentrate Potassium in trk1Δtrk2Δ Yeast, Jennifer Hou, Page N. Daniels, and Martin D. Burke ACS Chemical Biology 2020, 15 (6), 1575-1580 DOI: 10.1021/acschembio.0c00180

52. Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia. Katrina A. Muraglia, Rajeev S. Chorghade, Bo Ram Kim, Xiao Xiao Tang, Viral S. Shah, Anthony S. Grillo, Page N. Daniels, Alexander G. Cioffi, Philip H. Karp, Lingyang Zhu, Michael J. Welsh and Martin D. Burke Nature 2019, 567, 405–408 DOI: 10.1038/s41586-019-1018-5

51.Modular Syntheses of Phenanthroindolizidine Natural Products Young-In Jo, Martin D. Burke, and Cheol-Hong Cheon Organic Letters 2019, 21 (11), 4201-4204 DOI: 10.1021/acs.orglett.9b01397

50. Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp3 boronic acids, Jonathan W. Lehmann, Ian T. Crouch, Daniel J. Blair, Melanie Trobe, Pulin Wang, Junqi Li and Martin D. Burke Nature Communications 2019, 10, 1263 DOI: 10.1038/s41467-019-09249-z

49. Peridinin Is an Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation Hannah M. S. Haley, Adam G. Hill, Alexander I. Greenwood, Eric M. Woerly, Chad M. Rienstra, and Martin D. Burke Journal of the American Chemical Society 2018, 140 (45), 15227-15240 DOI: 10.1021/jacs.8b06933

48. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity, Yvette Y Yien, Jiahai Shi, Caiyong Chen, Jesmine T M Cheung, Anthony S Grillo, Rishna Shrestha, Liangtao Li 6, Xuedi Zhang 7, Martin D Kafina, Paul D Kingsley, Matthew J King, Julien Ablain, Hojun Li, Leonard I Zon, James Palis, Martin D Burke, Daniel E Bauer, Stuart H Orkin, Carla M Koehler, John D Phillips, Jerry Kaplan, Diane M Ward, Harvey F Lodish and Barry H Paw Journal of Biological Chemistry 2018293, 19797-19811. DOI:  10.1074/jbc.RA118.002742

47. Towards the generalized iterative synthesis of small molecules. Jonathan W. Lehmann, Daniel J. Blair and Martin D. Burke Nature Reviews Chemistry 2018, 2, 0115 DOI: 10.1038/s41570-018-0115

46. The molecular industrial revolution: automated synthesis of small molecules, Melanie Trobe and Martin D Burke Angewandte Chemie 2018, 57, 4192-4214 DOI: 10.1002/anie.201710482

45. Solid-State NMR of highly 13C-enriched cholesterol in lipid bilayers Lisa A Della Ripa, Zoe A Petros, Alexander G Cioffi, Dennis W Piehl, Joseph M Courtney, Martin D Burke and Chad M Rienstra Methods 2018, 138-139; 47-53. DOI: 10.1016/j.ymeth.2018.01.00

44. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals Anthony S. Grillo, Anna M. SantaMaria, Martin D. Kafina, Alexander G. Cioffi, Nicholas C. Huston, Murui Han, Young Ah Seo, Yvette Y. Yien, Christopher Nardone, Archita V. Menon, James Fan, Dillon C. Svoboda, Jacob B. Anderson, John D. Hong, Bruno G. Nicolau, Kiran Subedi, Andrew A. Gewirth, Marianne Wessling-Resnick, Jonghan Kim, Barry H. Paw and Martin D. Burke Science,  2017, 356 608-615. DOI: 10.1126/science.aah3862

43. The natural productome, Andrea M. E. Palazzolo, Claire L. W. Simons, Martin D. Burke Proceedings of the National Academy of Sciences 2017, 114 (22) 5564-5566; DOI: 10.1073/pnas.1706266114

42. MIDA Boronates Are Hydrolysed Fast and Slow by Two Different Mechanisms” Gonzalez, J.A; Maduka Ogba, O.; Morehouse, G.F.; Rosson, N.; Houk, K.N.; Leach, A.G.; Cheong, P.H.Y.; Burke, M.D.; Lloyd-Jones, G.C. Nature Chemistry 2016, 8, 1067-1075. DOI: 10.1038/nchem.2571

41. Our Path to Less Toxic Amphotericins, Endo, M.M.; Cioffi, A.G.; Burke, M.D. Synlett 2015, 27, 337. DOI: 10.1055/s-0035-1560800 Recipient of the Thieme IUPAC Prize in Synthetic Organic Chemistry.

40. C3-OH of Amphotericin B Plays an Important Role in Ion Conductance, Stephen A. Davis, Lisa A. Della Ripa, Lingbowei Hu, Alexander G. Cioffi, Taras V. Pogorelov, Chad M. Rienstra, and Martin D. Burke Journal of the American Chemical Society 2015 137 (48), 15102-15104 DOI: 10.1021/jacs.5b05766

39.Restored Physiology in Protein-Deficient Yeast by a Small Molecule Channel Alexander G. Cioffi, Jennifer Hou, Anthony S. Grillo, Katrina A. Diaz, and Martin D. Burke Journal of the American Chemical Society 2015 137 (32), 10096-10099 DOI: 10.1021/jacs.5b05765

38. Nontoxic Antimicrobials that Evade Drug Resistance Davis, S. A.; Vincent, B. M.; Endo, M. M.; Whitesell, L.; Marchillo, K.; Andes, D. R.; Lindquist, S.; Burke, M. D. Nature Chemical Biology 2015, 11, 481-487. DOI: 10.1038/nchembio.1821

37. Synthesis of many different types of organic small molecules using one automated process, Junqi Li, Steven G. Ballmer, Eric P. Gillis, Seiko Fujii, Michael J. Schmidt, Andrea M. E. Palazzolo, Jonathan W. Lehmann, Greg F. Morehouse, and Martin D. Burke Science 2015, 347, 1221-1226 DOI: 10.1126/science.aaa5414

36. From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks Junqi Li, Anthony S. Grillo, and Martin D. Burke. Accounts of Chemical Research 2015 48 (8), 2297-2307 DOI: 10.1021/acs.accounts.5b00128

35. Synthesis of Most Polyene Natural Product Motifs Using Just Twelve Building Blocks and One Coupling Reaction, Woerly, E. M.; Roy, J.; Burke, M. D. Nature Chemistry 2014, 6, 484-491.
DOI: 10.1038/nchem.1947

34. Amphotericin Forms an Extramembranous and Fungicidal Sterol Sponge, Anderson, T. M.; Clay, M. C.; Cioffi, A. G.; Diaz, K. A.; Hisao, G. S.; Tuttle, M. D.; Nieuwkoop, A. J.; Comellas, G.; Wang, S.; Uno, B. E.; Wildeman, E. L.; Maryum, N.; Gonen, T.; Rienstra, C. M.; Burke, M. D. Nature Chemical Biology 2014, 10, 400-406. DOI: 10.1038/nchembio.1496

33. C2′-OH of Amphotericin B Plays an Important Role in Binding the Primary Sterol of Human Cells but Not Yeast Cells, Brandon C. Wilcock, Matthew M. Endo, Brice E. Uno, and Martin D. Burke Journal of the American Chemical Society 2013 135 (23), 8488-8491 DOI: 10.1021/ja403255s

32. (1-Bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Eric M. Woerly, Jonathan E. Miller, and Martin D. Burke Tetrahedron 2013, 69, 7732-7740. DOI: 10.1016/j.tet.2013.05.050 

31. Electronic tuning of site-selectivity, Brandon C Wilcock 1, Brice E Uno, Gretchen L Bromann, Matthew J Clark, Thomas M Anderson and Martin D Burke Nature Chemistry 2012, 4, 996-1003. DOI: 10.1038/nchem.1495

30. Amphotericin primarily kills yeast by simply binding ergosterol, Kaitlyn C. Gray, Daniel S. Palacios, Ian Dailey, Matthew M. Endo, Brice E. Uno, Brandon C. Wilcock, and Martin D. Burke Proceedings of the National Academy of Sciences U.S.A. 2012, 109, 2234-223 DOI: 10.1073/pnas.1117280109

29. A General Solution for the 2-Pyridyl Problem Graham R. Dick,Eric M. Woerly and Martin D. Burke, Angewandte Chemie International Edition 2012, 51, 2667-2672 DOI: 10.1002/anie.201108608

28. Pinene-Derived Iminodiacetic Acid (PIDA): A Powerful Ligand for Stereoselective Synthesis and Iterative Cross-Coupling of C(sp3) Boronate Building Block Junqi Li and Martin D. Burke Journal of the American Chemical Society 2011, 133 (35), 13774-13777 DOI: 10.1021/ja205912y

27. Total Synthesis of Synechoxanthin through Iterative Cross-Coupling, Seiko Fujii,Stephanie Y. Chang and Martin D. Burke Angewandte Chemie International Edition 2011, 50, 7862-7864. DOI: 10.1002/anie.201102688

26. Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities, Daniel S. Palacios, Ian Dailey, David M. Siebert, Brandon C. Wilcock, and Martin D. Burke Proceedings of the National Academy of Sciences U.S.A. 2011, 108, 6733-6738. DOI: 10.1073/pnas.1015023108

25. (Z)-(2-Bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Eric M. Woerly, Justin R. Struble, Nagarjuna Palyam, Sean P. O’Hara, and Martin D. Burke Tetrahedron 2011, 67, 4333-4343. DOI: 10.1016/j.tet.2011.04.021 

24. Stereoretentive Suzuki−Miyaura Coupling of Haloallenes Enables Fully Stereocontrolled Access to (−)-Peridinin Eric M. Woerly, Alan H. Cherney, Erin K. Davis, and Martin D. Burke Journal of the American Chemical Society 2010, 132 (20), 6941-6943 DOI: 10.1021/ja102721p 

23. A Simple and General Platform for Generating Stereochemically Complex Polyene Frameworks by Iterative Cross-Coupling Suk Joong Lee,Thomas M. Anderson,Prof. Martin D. Burke Angewandte Chemie International Edition 2010, 49, 8860-8863. DOI: 10.1002/anie.201004911

22. A General Method for Synthesis of 2-Heterocyclic N-Methyliminodiacetic Acid Boronates Graham R. Dick, David M. Knapp, Eric P. Gillis, and Martin D. Burke Organic Letters 2010, 12 (10), 2314-2317 DOI: 10.1021/ol100671v

21. N-(Carboxymethyl)-N-methyl-glycine Ian Dailey and Martin D.Burke Encyclopedia of Reagents for Organic Synthesis 2010, DOI: 10.1002/047084289X.rn01228

20. Ethynyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis, Graham R. Dick, David M. Knapp, Eric P. Gillis, and Martin D. Burke Tetrahedron 2010, 66, 4710-4718 DOI: 10.1016/j.tet.2010.04.020

19. A general solution for unstable boronic acids: Slow-release cross-coupling from air-stable MIDA boronates, David M. Knapp, Eric P. Gillis, Martin D. Burke Journal of the American Chemical Society, 2009 131(20), 6961-6963 DOI: 10.1021/ja901416p

–        For Prof. Richard Taylor’s application of this methodology in the total synthesis of dictyosphaeric acid A, see Angewandte Chemie International Edition 2010, 49, 5574-5577.

–        For Prof. Jon Ellman’s recent development of asymmetric additions to aldimines via slow-release with MIDA boronates, see The Journal of Organic Chemistry 2010, 75, 3147-3150.

–        For an application of this latter methodology to the total synthesis of aurantioclavine, see Organic Letters 2010, 12, 2004-2007.

18. Iterative Cross-Couplng with MIDA Boronates: Towards a General Platform for Small Molecule Synthesis, Eric P. Gillis and Martin D. Burke Aldrichimica Acta. 2009, 42(1): 17–27. DOI: 10.1002/0471264229.os086.33

17. Flexible tetracycline synthesis yields promising antibiotics Martin D Burke Nature Chemical Biology 2009, 5, 77-79 DOI: 10.1038/nchembio0209-77

16. Vinyl MIDA Boronate: a readily accessible and highly versatile building block for small molecule synthesis, Brice E. Uno, Eric P. Gillis, Martin D. Burke Tetrahedron 2009, 65, 3130-3138 DOI: 10.1016/j.tet.2010.04.020

Special Issue dedicated to Professor Justin Dubois’ receipt of the 2008 Tetrahedron Young Investigator Award

15. B-Protected Haloboronic Acids for Iterative Cross-Coupling, Steven G. Ballmer, Eric P. Gillis, Martin D. Burke, Daniel Morton and Huw M L Davies Organic Syntheses 2009, 86, 344-359 DOI: 10.1002/0471264229.os086.33

14. Multistep Synthesis of Complex Boronic Acids from Simple MIDA Boronates,  Eric P. Gillis and Martin D. Burke Journal of the American Chemical Society 2008, 130 (43), 14084-14085 DOI: 10.1021/ja8063759

13. Simple, Efficient, and Modular Syntheses of Polyene Natural Products via Iterative Cross-Coupling Suk Joong Lee, Kaitlyn C. Gray, James S. Paek, and Martin D. Burke Journal of the American Chemical Society 2008, 130 (2), 466-468 DOI: 10.1021/ja078129x

12. A Post-PKS Oxidation of the Amphotericin B Skeleton Predicted to be Critical for Channel Formation Is Not Required for Potent Antifungal Activity Daniel S. Palacios, Thomas M. Anderson, and Martin D. Burke Journal of the American Chemical Society 2007, 129 (45), 13804-13805 DOI: 10.1021/ja075739o

11. A Simple and Modular Strategy for Small Molecule Synthesis:  Iterative Suzuki−Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks Eric P. Gillis and Martin D. Burke Journal of the American Chemical Society 2007, 129 (21), 6716-6717 DOI: 10.1021/ja0716204

10. Molecular Prosthetics: Replicating the Functions of the Molecules of Life Martin D. Burke Enhancing Chemistry Conference sponsored by the American Chemical Society. University of Illinois at Urbana-Champaign, Urbana, Illinois, March 17, 2006.

9. A Synthesis Strategy Yielding Skeletally Diverse Small Molecules Combinatorically, Martin D. Burke, Eric M. Berger, and Stuart L. Schreiber Journal of the American Chemical Society 2004 126 (43), 14095-14104 DOI: 10.1021/ja0457415

8. A planning strategy for diversity-oriented synthesis Martin D. Burke and Stuart L. Schreiber Angewandte Chemie International Edition 2004, 43, 46-58. DOI: 10.1002/anie.200300626

7. Generating Diverse Skeletons of Small Molecules Combinatorially Martin D. Burke, Eric M. Berger, and Stuart L. Schreiber Science 2003, 302, 613-618 DOI: 10.1126/science.1089946 

6. Chemoenzymatic Route to Macrocyclic Hybrid Peptide/Polyketide-like Molecules Rahul M. Kohli, Martin D. Burke, Junhua Tao, and Christopher T. Walsh Journal of the American Chemical Society 2003, 125 (24), 7160-7161 DOI: 10.1021/ja0352202

5. Teaching Target-Oriented and Diversity-Oriented Organic Synthesis at Harvard University. Martin D. Burke and Gojko Lalic Chemistry and Biology 2002, 9, 535-541. DOI: 10.1016/S1074-5521(02)00143-6

4. Conformationally restricted hybrid analogues of the hormone 1 alpha,25-dihydroxyvitamin D(3): design, synthesis, and biological evaluation, M.C. White, M.D. Burke, S. Peleg, P. Dolan, T. Kensler, H. Brem, and G.H. Posner Bioorganic & Medicinal Chemistry 2001, 9, 1691-1699 DOI: 10.1016/s0968-0896(01)00087-6

3. Central Nervous System, Drug Delivery to Treat, M.D. Burke, H. Brem, and R. Langer In The Encyclopedia of Controlled Drug Delivery The Encyclopedia of Controlled Drug Delivery.  Mathiowitz, E., Ed.; John Wiley and Sons., Vol. 1, 1999, 184-212.

2. Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation Gary H. Posner, Jae Kyoo Lee, Qiang Wang, Sara Peleg, Martin Burke, Henry Brem, Patrick Dolan, and Thomas W. Kensler Journal of Medicinal Chemistry 1998, 41 (16), 3008-3014 DOI: 10.1021/jm980031t

1.Polymer-Controlled Drug Delivery: An Overview for the Clinician, J. Hanes and M.D. Burke.  Hospital Pharmacist Report.  December 1997 2-11.